Broadening the Frontline—Studies Informing the Use of Immunotherapy in Hepatocellular Carcinoma

Release Date: August 26, 2025

Expiration Date: August 26, 2026

Activity Overview

Immunotherapy-based approaches have fundamentally transformed the management of unresectable hepatocellular carcinoma (HCC). However, questions related to appropriate patient selection, therapy sequencing, and the role of immunotherapy in the non-advanced disease settings have remained unanswered. In this program, expert faculty in the management of HCC provide recent updates on the use of established immunotherapy-based treatment approaches for HCC, with an emphasis on the treatment of patients who have traditionally fallen outside the inclusion criteria of pivotal clinical trials.

Target Audience

This educational activity is directed toward US-based medical oncologists, gastrointestinal (GI) oncologists, advanced practice providers, nurses, and other health care professionals who treat patients with GI cancers.

Learning Objectives

Upon successful completion of this activity, you should be better prepared to:

• Evaluate immune-based treatment strategies for advanced hepatobiliary cancers and their applicability to diverse patient populations, including those with hepatic dysfunction or poor performance status.
• Apply recent evidence to inform treatment selection, sequencing, and delivery of immunotherapy in hepatocellular and biliary tract cancers across frontline and emerging therapeutic settings.

Faculty, Staff, and Planners’ Disclosures

The staff of Physicians’ Education Resource^®, LLC have no relevant financial relationships with ineligible companies.

PER^® mitigated all COI for faculty, staff, and planners prior to the start of this activity by using a multistep process.

Off-Label Disclosure and Disclaimer

This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this accredited activity is for continuing education purposes only and is not meant to substitute for the independent clinical judgment of a health care professional relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER^® or any company that provided commercial support for this activity.