Release Date: December 23, 2025
Expiration Date: December 23, 2026
Activity Overview
This educational activity is an archive of the live presentation held on Monday, December 8, 2025.
For more information about this educational activity, the faculty, and disclosures, please click here.
Target Audience
This educational activity is directed toward medical oncologists, advanced practice providers, nurses, and other health care professionals involved in the treatment and management of metastatic breast cancer.
Learning Objectives
Upon successful completion of this activity, you should be better prepared to:
- Interpret recent clinical trial data evaluating new therapies and novel combinations for the treatment of HR+/HER2- metastatic breast cancer (MBC)
- Develop individualized treatment plans that utilize targeted therapies for patients with endocrine-sensitive HR+/HER2- MBC
- Incorporate the best available evidence to select and sequence antibody-drug conjugates for the treatment of endocrine-resistant HR+/HER2-low MBC
- Implement strategies to manage treatment-related adverse events and support adherence through patient education and shared decision-making

Erika P. Hamilton, MD
Director, Breast Cancer Research Program
Chair, Breast Executive Committee
Sarah Cannon Research Institute
Nashville, TN

Giuseppe Curigliano, MD, PhD
Professor of Medical Oncology
University of Milan
Director, Early Drug Development Division
European Institute of Oncology
Milan, Italy

VK Gadi, MD, PhD
Professor of Clinical Medicine
Division of Hematology and Oncology
University of Illinois Cancer Center
Director, Medical Oncology
University of Illinois College of Medicine
Chicago, IL

Jason Aboudi Mouabbi, MD
Assistant Professor, Department of Breast Medical Oncology
Division of Cancer Medicine
The University of Texas MD Anderson Cancer Center
Houston, TX
Faculty, Staff, and Planners’ Disclosures
The staff of Physicians’ Education Resource®, LLC (PER®) have no relevant financial relationships with ineligible companies.
PER mitigated all COI for faculty, staff, and planners prior to the start of this activity.
Off-Label Disclosure and Disclaimer
This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this accredited activity is for continuing education purposes only and is not meant to substitute for the independent clinical judgment of a health care professional relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER or any company that provided commercial support for this activity.

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