Activity Overview
This online, on-demand virtual symposium brings together renowned experts in HR+/HER2– metastatic breast cancer. In this educational program, these experts review recent clinical findings, discuss their potential implications for current practice, and provide actionable guidance for optimizing patient care.
This
educational activity is an archive of the live symposium held on May
27, 2026.
Target Audience
Medical
oncologists, advanced practice providers, nurses, and other health care
providers who are involved in the management of patients with advanced or
metastatic breast cancer.
Learning Objectives
Upon successful completion of this activity, you should be better prepared to:
- Identify approved and emerging oral SERDs for the management of HR+/HER2– breast cancer.
- Assess emerging clinical trial and real-world evidence to gain practical insights into the appropriate use of oral SERD-based treatment strategies for patients with HR+/HER2– MBC.
- Integrate clinical trial data, real-world evidence, and patient- and disease-specific factors to inform personalized treatment decisions for patients with HR+/HER2– MBC.

Hope S. Rugo, MD, FASCO
Director, Women’s Cancers Program
Division Chief, Breast Medical Oncology
Professor, Department of Medical Oncology & Therapeutics
Research
City of Hope Comprehensive Cancer Center
Duarte, CA
Professor Emeritus, UCSF
Disclosures: Consulting or Advisory Role: BioNTech, Bristol Myers Squibb, Helsinn, Napo; Grant/Research Funding (to prior institution, UCSF): Ambryx, AstraZeneca, Daiichi Sankyo, Inc, F. Hoffmann-La Roche/Genentech, Gilead Sciences, Inc, Lilly, Merck & Co, Novartis Pharmaceuticals, Pfizer, Stemline Therapeutics; Grant/Research Funding (to current institution, COH): Bicycle Therapeutics, F. Hoffmann-La Roche/Genentech, Merck & Co, Stemline Therapeutics

Fabrice André, MD, PhD
Head of Research
Professor, Department of Medical Oncology
Gustave Roussy, Université Paris-Saclay
Villejuif, France
Disclosures: Honorarium: AstraZeneca, Daiichi Sankyo, Lilly, Novartis, Relay Therapeutics; Research Grants or Advisory Boards (paid to institution): AstraZeneca, Bristol Myers Squibb, Daiichi Sankyo, Lilly, Novartis, Pfizer, Relay Therapeutics, Roche

Heather McArthur, MD, MPH
Professor of Internal Medicine
Clinical Director, Breast Cancer Program
Komen Distinguished Chair in Clinical Breast Cancer Research
UT Southwestern Medical Center
Dallas, TX
Disclosures: Consultant: Amgen, Arvinas, AstraZeneca, Bristol Myers Squibb, Calithera, Celgene, Daiichi Sankyo, Genentech/Roche, Immunomedics, Lilly, Merck, OBI Pharma, Peregrine, Pfizer, Puma, Seattle Genetics, Spectrum Pharmaceuticals, Syndax Pharmaceuticals, TapImmune; Grant/Research Support: Bristol Myers Squibb, BTG, MedImmune/AstraZeneca, Merck

Nadia Harbeck, MD
Director, Breast Center
Department of Obstetrics and Gynecology
LMU University Hospital
Munich, Germany
Disclosures: Consulting/Advisory Role: Daiichi-Sankyo, IQVIA, Novartis, Pfizer, Roche/Genentech; Speakers Bureau: Amgen, AstraZeneca, Daiichi-Sankyo, Exact Sciences, Lilly, Menarini-Stemline, Merck, Sharpe & Dohme, Novartis, Pfizer, Pierre Fabre, Roche, Viatris, Zuellig Pharma; Research Funding (Institutional): AstraZeneca, Lilly, Merck, Sharpe & Dohme, Novartis, Pfizer, Roche/Genentech; Stock/Ownership: WSG (Women’s Cancer Study Group)
The staff of Physicians’ Education Resource®, LLC have no relevant financial relationships with ineligible companies.
PER® mitigated all COI for faculty, staff, and planners prior to the start of this activity by using a multistep process.
Off-Label Disclosure and Additional Disclaimers
This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this accredited activity is for continuing education purposes only and is not meant to substitute for the independent clinical judgment of a health care professional relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER® or any company that provided commercial support for this activity.
This accredited activity has been developed in accordance with applicable accreditation standards to ensure balance, independence, objectivity, and scientific rigor. Faculty were instructed to use generic names where possible and to base recommendations on the best available evidence.
In the context of clinical discussion, proprietary product names may be mentioned. Such references are made for educational purposes only and do not constitute endorsement of any commercial product or service.
Learners are encouraged to independently evaluate the information
presented and apply their own clinical judgment when considering patient care
decisions.
