Release Date: September 30, 2025
Expiration Date: September 30, 2026
Activity Overview
Vaccine hesitancy is a complex and multifaceted issue shaped by individual beliefs, cultural and societal norms, trust in health care systems, and broader social determinants of health. A significant driver of vaccine hesitancy is concern about adverse events, including both anticipated and previously experienced events, although many other barriers can hinder vaccine uptake. This program provides expert insights and interactions with a simulated patient to highlight opportunities for health care providers to address adult patients’ barriers to vaccine acceptance.
Target Audience
This educational activity is directed toward internists/primary care clinicians, family medicine physicians, pharmacists, nurse practitioners, physician assistants, registered nurses, and other health care providers involved in the administration of adult immunization.
Learning Objectives
Upon successful completion of this activity, you should be better prepared to:
- Summarize key barriers that undermine adherence to recommended adult immunization schedules.
- Explain key concepts in vaccinology to support informed clinical decision-making.
- Implement evidence-based strategies to increase vaccine uptake among eligible adults

Charles Vega, MD
Clinical Professor
Department of Family Medicine
Assistant Dean for Culture and Community Education
UC Irvine School of Medicine
Irvine, CA
Disclosures: Consultant: Boehringer Ingelheim, Exact Sciences
Faculty, Staff, and Planners’ Disclosures
The staff of Physicians’ Education Resource®, LLC have no relevant financial relationships with ineligible companies.
PER® mitigated all COI for faculty, staff, and planners prior to the start of this activity by using a multistep process.
Off-Label Disclosure and Disclaimer
This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this accredited activity is for continuing education purposes only and is not meant to substitute for the independent clinical judgment of a health care professional relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER® or any company that provided commercial support for this activity.

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