Burst CME™: Optimal Management of Complications of Sickle Cell Disease

Release Date: December 23, 2025

Expiration Date: December 23, 2026

Activity Overview

This educational program for hematologists delivers a practical, evidence-based update on the management of pain and other common complications in patients with sickle cell disease (SCD). The curriculum emphasizes both acute and chronic pain across the lifespan, integrating current guideline recommendations with emerging disease-modifying and complication-directed strategies. Expert faculty with extensive clinical experience in SCD care review the underlying pathophysiology of vaso-occlusion and chronic pain syndromes, while addressing real-world challenges such as opioid stewardship and individualized pain plans. The program also covers the prevention and management of key SCD-related complications, including acute chest syndrome, stroke, infection, and priapism. Through data-driven presentations and case-based discussion, clinical experts share insights drawn from years of treating patients with SCD, highlighting how trial evidence, guidelines, and lived clinical experience intersect in everyday practice. Participants will gain actionable strategies to optimize pain control, reduce complications, and improve quality of life for patients with SCD within contemporary hematology care models.

Target Audience

This educational activity is primarily directed toward hematologists, NPs, and PAs. Other clinicians involved in the care of SCD will also be invited to participate.

Learning Objectives

Upon successful completion of this activity, you should be better prepared to:

• Design individualized plans for managing pain and other complications in patient with SCD.

The staff of Physicians’ Education Resource^®, LLC have no relevant financial relationships with ineligible companies.

PER^® mitigated all COI for faculty, staff, and planners prior to the start of this activity by using a multistep process.

Off-Label Disclosure and Disclaimer

This activity may or may not discuss investigational, unapproved, or off-label use of drugs. Learners are advised to consult prescribing information for any products discussed. The information provided in this accredited activity is for continuing education purposes only and is not meant to substitute for the independent clinical judgment of a health care professional relative to diagnostic, treatment, or management options for a specific patient’s medical condition. The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of PER^® or any company that provided commercial support for this activity.